EQuIS Research


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Publications



Daodu OO, Zondervan N, Urban D, Bain P, MacRobie A, Brindle ME. “Deriving literature-based benchmarks for pediatric appendectomy and cholecystectomy complications from national databases in high-income countries: A systematic review” Journal of Pediatric Surgery, September 2019.


Jancelewicz T, Brindle ME. “Prediction Tools in Congenital Diaphragmatic Hernia” Seminars in Perinatology, July 2019.


Jancelewicz T, Brindle ME, Guner YS, Lally PA, Lally KP, Harting MT, Pediatric Surgery Research Collaborative, Congenital Diaphragmatic Hernia Study Group. “Towards Standardized Management of Congenital Diaphragmatic Hernia: An Analysis of Practice Guidelines” Journal of Surgical Research 243:226-235, 2019.


Rove KO, Brockel MA, BrindleME, Scott MJ, Herndon A, Ljungqvist O, Koylye MA. “Embracing Change- The Time for Pediatric ERAS is Now” Journal of Pediatric Urology, April 2019.


Brindle ME, Heiss K, Scott MJ, Herndon AC, Ljungqvist O, Koyle M. “Embracing the Change- The Era for ERAS is Here” Pediatric Surgery International 35(6):631-634, April 2019.


Naqvi SA, Thompson GC, Joffe AR, Blackwood J, Martin DA, Brindle M, Barkema HW, Jenne CN. “Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators” Mediators of Inflammation, Feb 2019.


Yang MMH, Hader W, Bullivant K, Brindle M, Riva-Cambrin J. “Calgary Shunt Protocol, an adaption of the Hydrocephalus Clinical Research Network shunt protocol, reduces shunt infections in children” Journal of Neurosurgery: Pediatrics, Feb 2019.


Gimon T, Almosallam O, Lopushinsky S, Brindle M, Yanchar NL. “Optimizing Post-Operative Follow-up in Pediatric Surgery” Journal of Pediatric Surgery, Feb 2019.


Gibb A, Crosby MA, McDiarmid C, Urban D, Lam JYK, Wales PW, Brockel M, Raval M, Offringa M, Skarsgard E, Wester T, Wong K, de Beer D, Nelson G, Brindle ME “Creation of an Enhanced Recovery After Surgery (ERAS) Guideline for Neonatal Intestinal Surgery Patients: A Knowledge Synthesis and Consensus Generation and Protocol Study” BMJ Open, 8(12), December 2018


Jancelewicz T, Brindle ME, Harting MT, Tolley EA, Langham MR, Lally PA, Gosain A, Storgian SA, Kays DW “Extracorporeal Membrane Oxygenation (ECMO) risk stratification in newborns with Congenital Diaphragmatic Hernia (CDH)” Journal of Pediatric Surgery, April 2018


Brindle ME, Henrich N, Foster A, Marks S, Rose M, Welsh R, Berry W “Implementation of Surgical Debriefing Programs in Large Health Systems: An Exploratory Qualitative Analysis” BMC Health Services Research, On line March 2018


Shommu NS, Jenne CN, Blackwood J, Martin DA, Joffe AR, Eccles R, Brindle M, Khanafer I, Vogel HJ, Thompson GC. The Use of Metabolomics and Inflammatory Mediator Profiling Provides a Novel Approach to Identifying Pediatric Appendicitis in the Emergency Department. Scientific reports. Mar 6;8(1):4083. 2018


Harting MT, Hollinger L, Tsao K, Putnam LR, Wilson JM, Hirschl RB, Skarsgard ED, Tibboel D, Brindle ME, Lally PA, Miller CC, Kally KP “Aggressive surgical management of congenital diaphragmatic hernia - worth the effort? A multi-center, prospective, cohort study” Annals of Surgery, February 2018.


Sigalet DL, Lam V, Brindle M, Boctor D, Wallace L, de Heuval E, Hartmann B, Holst JJ “The Glucagon Like Peptide-2 ‘Axis’: Capacity for Production and Response Following Intestinal Resection or Repair of Gastroschisis in Infants” Journal of Pediatric Surgery, On line February 2018


TCCDH Collaborative (Brindle ME co-author) “Diagnosis and management of congenital diaphragmatic hernia: A clinical practice guideline” Canadian Medical Association Journal (CMAJ) 190 (4) e103; January 2018


Shawyer AC, Roberts A, Connolly BL, Yang CL, Stoain CA, Cohen E, Ratjen F, Maclusky I, Walton JM, Thorpe K, Giglia L, Brindle M, Livingston MH, Hamdani M, Mahant S, Parsons SJ, Laberge S “Intrapleural Dornase and Tissue Plasminogen Activator in pediatric empyema (DTPA): a study protocol for a randomized controlled trial” Trials. 18(1);293. 2017


Lagoo J, Lopushinsky SR, Haynes AB, Bain P, Flageole H, Skarsgard ED, Brindle ME “The Effectiveness of Pediatric Surgical Safety Checklists: A Systematic Review with Narrative Synthesis” BMJ Open. 7(10); Online October 2017


Lai SW, de Heuvel E, Wallace LE, Hartmann B, Holst JJ, Brindle ME, Chelikani PK, Sigalet DL “Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats”. PLOS ONE. 12(7) Online July 2017


Gunasekara L, Mustafa A-S, Green F, Pratt R, Bjornson C, Yang A, Schoel WMS, Brindle M, Montgomery M, Keys E, Dennis J, Shrestha G, Amrein M "Pulmonary surfactant dysfunction in pediatric cystic fibrosis: Mechanisms and reversal with a lipid-sequestering drug." Journal of Cystic Fibrosis. Online June 2017.


Holmes EM, Singh HHK, Kirk VG, Brindle M, Luntley J, Weber BA, Yunker WK “Incidence of children at risk for obstructive sleep apnea undergoing common day surgery procedures” Journal of Pediatric Surgery. Online May 2017.


Sigalet DL, Brindle ME, Boctor D, Lam V, Lu LS, de Heuvel E, Hartmann B, Holst JJ “A safety and pharmacokinetic dosing study of glucagon-like peptide 2 in infants with intestinal failure” Journal of Pediatric Surgery 52(5); 749-754, 2017


Hall N, Simon E, Abbo L, Arnaud A, Beaudin M, Brindle M, et al. “Appendectomy versus non-operative treatment for acute uncomplicated appendicitis in children: study protocol for a multicenter, open-label, non-inferiority, randomized controlled trial” BMJ Paediatrics Open. Online May 2017.


Brindle ME, Roberts D, Daodu O, Haynes A, Cauley C, Dixon E, LaFlamme C, Bain P, Berry W “Deriving literature-based benchmarks for surgical complications in high-income countries: A protocol for a systematic review and meta-analysis” BMJ Open. Online May 2017


Daodu O, Brindle ME “Predicting Outcomes in Congenital Diaphragmatic Hernia” Seminars in Pediatric Surgery. Online April 2017


Daodu O, Brindle M, Alvarez-Allende CR, Lockyer L, Weber B, Lopushinsky SR “Outcomes of an accelerated care pathway for pediatric blunt solid organ injuries in a public healthcare system” Journal of Pediatric Surgery Online January 2017


Urban D, Dehaeck R, Lorenzetti D, Guilfoyle J, Poon M-C, Steel M, Lardner D, Ma IWY, Brindle ME “The safety and efficacy of tranexamic acid in bleeding paediatric trauma patients: A systematic review protocol”. BMJ Open Sept 22; 6:e012947, 2016


Khanafer I, Martin D-A, Mitra TP, Eccles R, Brindle ME, Nettel-Aguirre A, Thompson G “Test characteristics of common appendicitis scores with and without laboratory investigations: a prospective observational study”. BMC Pediatrics Aug 30; 16(1):147, 2016.


Shariff F, Peters PA, Arbour L, Greenwood M, Skarsgard ED, Brindle ME “Maternal and community predictors of gastroschisis and congenital diaphragmatic hernia in Canada”. Pediatric Surgery International Sept;1-6, 2015.


Sanchez-Glanville C, Brindle ME, Spence T, Blackwood J, Drews T, Menzies S, Martin S, Lopushinsky SR “Evaluating the introduction of extracorporeal life support technology to a tertiary-care pediatric institution: smoothing the learning curve through inter-professional simulation training”. Journal of Pediatric Surgery. May; 50(5):798-804, 2015.


Brindle ME, Cook EF, Tibboel D, Lally P, Lally K “A clinical prediction rule for the severity of congenital diaphragmatic hernias in newborns”. Pediatrics. Aug; 134(2) e413-e419 2014. (Identified by the Outcomes and Evidence-based Practice Committee as a recommended paper to help identify best practice and appropriate standards)


Peer-reviewed EQuIS Abstracts

Shawyer A, Rajapakse N, Brindle M, Vayalumkal JV. "Prophylactic antibiotics in appendicitis - Are we getting the timing right?" Open Forum Infectious Diseases 3(suppl 1): 1447. 2016.



Presentations





2017 MacRobie A, Harrop AR, Lardner D, Brauer C, Brindle ME, Sartisan H “Improving Access for Urgent and Emergent Surgical Cases at the Alberta Children’s Hospital: A Realist Review”, Canadian Society of Epidemiology and Biostatistics. June 2017


2017 Abdullah H, Gibb A, Urban D, MacRobie A, Rivera L, Brindle ME “An Audit of Impanted-device Associated Infections at the Alberta Children’s Hospital: A Mixed Chart Review/Electronic Administrative Data Study”, Canadian Society of Epidemiology and Biostatistics. June 2017


2017 Rivera L, Urban D, MacRobie A, Gibb A, Abdullah A, Brindle ME “Tailoring the World Health Organization Surgical Safey Checklist to Pediatrics: An Implementation and Evaluation Study Protocol”, Canadian Society of Epidemiology and Biostatistics. June 2017


2016 Lagoo J, Lopushinsky SR, Haynes AB, Skarsgard ED, Flageole H, Brindle ME “Pediatric Surgical Safety Checklists: A Systematic Review with Narrative Synthesis”, Canadian Association of Paediatric Surgery. September 2016


2016 Daodu T, Brindle ME, Alvarez-Allende C, Lopushinsky “A solid organ injury protocol to decrease length of stay”, Canadian Association of Paediatric Surgery. September 2016​



EQuIS Research



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